In the course of the study, the Dr. Rath research team was able to show that the blocking of the collagen production by calcium antagonists can be compensated for by higher doses of vitamin C. In this process, vitamin C uses different paths and transport systems to enter the cells: diffusion (entering cells without any transport system), sodium channels or glucose transporters. If vitamin C blood concentrations are significantly increased due to higher uptakes of this vitamin, the influx of vitamin C into the cells via these paths is increased accordingly.
The most effective form of vitamin C for overcoming this blockage is its lipid-soluble form, ascorbyl palmitate, a compound of ascorbic acid and palmitic acid. Compared to pure vitamin C, it can overcome the blockage at around 40 times lower concentrations than other forms. Therefore, supplementing with ascorbyl palmitate will ensure that a sufficient amount of vitamin C is taken up by the cells to restore collagen production.
Pure vitamin C would have to be administered in extremely high doses in order to achieve the same effect. This dosage, however, cannot be achieved through oral administration. Another advantage of ascorbyl palmitate is its ability to use an additional path into the cell. Water- soluble vitamin C enters the cell via specific transport systems (e.g. calcium channels, sodium-potassium channels, glucose transporters). Fatsoluble vitamin C, by contrast, is able to pass through the outer cell layer – the lipid bilayer – without transporters. This is due to the fact that fatsoluble substances can move about freely in the fatty lipid bilayer.
Highly magnified collagen fiber. Three chains of collagen, represented here by blue, green and yellow structures, make up one collagen fiber. Collagen plays a similar role in our body to that of iron reinforcement rods in a skyscraper building.
The amount of collagen fibers produced in our body is largely dependent on the vitamin C intake from our diet.
Thus, an optimum micronutrient intake determines the proper function of collagen.
The study of the Dr. Rath Research Institute has shown two remarkable results: firstly, the administration of calcium channel blockers can lead to atherosclerosis and, ultimately, scurvy. Secondly, vitamin C, especially ascorbyl palmitate, is capable of reducing or neutralizing this devastating effect.
Needless to say, the present research results do not argue against the use of calcium antagonists, especially in patients with advanced cardiovascular disease. However, it is beyond any doubt that the administration of these drugs should mandatorily be combined with vitamin C and other micronutrients in order to prevent depletion in the cells of the vascular wall and resulting consequences.
In view of these results, it must be concluded that the administration of calcium antagonists is not justifiable without the simultaneous administration of vitamin C or rather ascorbyl palmitate and, therefore, must be referred to as medical malpractice.
This important information should make its way to every medical practice and open a major debate on the questionable use of calcium channel blockers.